Transforming
natural wealth
into sustainable and innovative health solutions
Outsourcing / CDMO
Innovation in Extract Development
Regulatory and Scientific Consulting
Research and Development of New Products
Technical-Regulatory Support for the Preparation of Dossiers and DMFs
Development and Validation of Analytical Methodologies
Agronomic services
Outsourcing / CDMO
We provide comprehensive contract manufacturing and development services, ensuring high-quality production and innovative solutions tailored to your needs.
- Manufacturing of Active Pharmaceutical Ingredients;
- Manufacturing of Food Ingredients;
- Manufacturing of Cosmetic Ingredients;
- Drying of Food Ingredients (SIF/MAPA);
- Extraction of Essential Oils;
- Planting, cultivation, and drying of plant species.
Innovation in Extract Development
We innovate in the development of plant extracts by combining knowledge from nature's wisdom with cutting-edge technology and scientific expertise. This way, we create effective and sustainable solutions for health and well-being.
- Scientific research on potential extracts;
- Extract development – Radical innovation;
- Extract development – Incremental innovation;
- Process development at bench and pilot scales;
- Technology transfer to the manufacturing area.
Regulatory and Scientific Consulting
To ensure high-level technical and regulatory support, we offer assistance in creating documents and files, along with specialized consulting in technology transfer and the regulation of herbal products.
- Consulting in pharmaceutical technology transfer processes;
- Consulting in the preparation of regulatory documents for international registrations;
- Consulting in the preparation of safety documents related to ingredient manufacturing;
- Regulatory consulting for the regulation of herbal medicines and specific pharmaceuticals.
Research and Development of New Products
With a manufacturing facility that includes a dedicated Research, Development, and Innovation site, and a team of masters and PhDs in Natural Products, we have the technological resources and expertise to accelerate product time-to-market. We utilize scientific tools such as Quality by Design (QbD), Design of Experiments, and AI-driven studies.
- Scientific research on potential extracts;
- Development of customized extracts;
- Process development at bench and pilot scales;
- Process optimization at bench scale through QbD.
Technical-Regulatory Support for the Preparation of Dossiers and DMFs
To ensure high-quality technical and regulatory support, we offer assistance in the preparation of dossiers and DMFs, along with specialized consulting in technology transfer and the regulation of herbal products.
- Consulting in pharmaceutical technology transfer processes;
- Consulting in the preparation of regulatory dossiers in CTD format (DMF, CEP, EDMF, ASMF, and Technical Package) for international registrations;
- Consulting in the preparation of GRAS safety dossiers (related to ingredient manufacturing);
- Regulatory consulting in the regulation of herbal medicines and specific pharmaceuticals (ANVISA).
Development and Validation of Analytical Methodologies
To ensure precise and reliable results in our specialized services for developing and validating analytical methodologies, we rely on a team of experts in chromatographic methods and use high-tech equipment to enhance the quality and efficiency of analytical processes. We adhere to national and international regulatory guidelines and standards, such as Anvisa, FDA, and ICH.
- Development and/or validation of analytical methodology by UV;
- Development and/or validation of analytical methodology by HPLC/UPLC;
- Development and/or validation of analytical methodology by GC;
- Scientific support in the preparation of protocols and analytical validation reports.
Agronomic services
At Centroflora, we operate in an integrated manner to ensure the quality, traceability, and sustainability of our botanical raw materials.
- Development of botanical supply chains;
- Development of specific cultivation practices and primary processing for each botanical species;
- Implementation of Good Agricultural Practices (GAP) for new crops;
- Prospection and agricultural technical visits to potential suppliers;
- Agricultural experimental studies.
